| NKI breast cancer clinical data {dynpred} | R Documentation |
Clinical and follow-up data of breast cancer patients as collected in the Dutch Cancer Institute (NKI) in Amsterdam
Description
A data frame of 295 patients with breast cancer. The included variables are
- patnr
Patient identification number
- d
Survival status; 1 = death; 0 = censored
- tyears
Time in years until death or last follow-up
- diameter
Diameter of the primary tumor
- posnod
Number of positive lymph nodes
- age
Age of the patient
- mlratio
Estrogen level?
- chemotherapy
Chemotherapy used (yes/no)
- hormonaltherapy
Hormonal therapy used (yes/no)
- typesurgery
Type of surgery (excision or mastectomy)
- histolgrade
Histological grade (Intermediate, poorly, or well differentiated)
- vasc.invasion
Vascular invasion (-, +, or +/-)
- crossval.clin.class
??
- PICV
Estrogen level?
Format
A data frame, see data.frame.
References
van't Veer LJ, Dai HY, van de Vijver MJ, He YDD, Hart AAM, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R \& Friend SH (2002). Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530–536.
van de Vijver MJ, He YD, van 't Veer LJ, Dai H, Hart AAM, Voskuil DW, Schreiber GJ, Peterse JL, Roberts C, Marton MJ, Parrish M, Atsma D, Witteveen A, Glas A, Delahaye L, van der Velde T, Bartelink H, Rodenhuis S, Rutgers ET, Friend SH \& Bernards R (2002). A gene-expression signature as a predictor of survival in breast cancer. New England Journal of Medicine 347, 1999–2009.
van Houwelingen HC, Bruinsma T, Hart AAM, van't Veer LJ \& Wessels LFA (2006). Cross-validated Cox regression on microarray gene expression data. Statistics in Medicine 25, 3201–3216.