Normalize & Denoise Droplet Single Cell Protein Data (CITE-Seq)


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Documentation for package ‘dsb’ version 0.3.0

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cells_citeseq_mtx small example CITE-seq protein dataset for 87 surface protein in 2872 cells
DSBNormalizeProtein Normalize single cell antibody derived tag (ADT) protein data with the DSBNormalizeProtein function. This single function runs step I (ambient protein background correction) and step II (defining and removing cell to cell technical variation) of the dsb normalization method. See <https://www.biorxiv.org/content/10.1101/2020.02.24.963603v3> for details of the algorithm.
empty_drop_citeseq_mtx small example CITE-seq protein dataset for 87 surface protein in 8005 empty droplets