Analysis of Dose-Response Curves


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Documentation for package ‘drc’ version 3.0-1

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A B C D E F G H I L M N O P R S T U V W Y

-- A --

acidiq Acifluorfen and diquat tested on Lemna minor.
actimL Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
algae Volume of algae as function of increasing concentrations of a herbicide
anova.drc ANOVA for dose-response model fits
AR.2 Asymptotic regression model
AR.3 Asymptotic regression model
auxins Effect of technical grade and commercially formulated auxin herbicides

-- B --

backfit Calculation of backfit values from a fitted dose-response model
baro5 The modified baro5 function
BC.4 The Brain-Cousens hormesis models
BC.5 The Brain-Cousens hormesis models
bcl3 The Brain-Cousens hormesis models
bcl4 The Brain-Cousens hormesis models
boxcox.drc Transform-both-sides Box-Cox transformation
braincousens The Brain-Cousens hormesis models
bread.drc Bread and meat for the sandwich

-- C --

cedergreen The Cedergreen-Ritz-Streibig model
chickweed Germination of common chickweed (_Stellaria media_)
chickweed0 Germination of common chickweed (_Stellaria media_)
CIcomp Calculation of combination index for binary mixtures
CIcompX Calculation of combination index for binary mixtures
coef.drc Extract Model Coefficients
comped Comparison of effective dose values
compParm Comparison of parameters
confint.drc Confidence Intervals for model parameters
cooks.distance.drc Model diagnostics for nonlinear dose-response models
CRS.4a The Cedergreen-Ritz-Streibig model
CRS.4b The Cedergreen-Ritz-Streibig model
CRS.4c The Cedergreen-Ritz-Streibig model
CRS.5a Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
CRS.5b Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
CRS.5c Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
CRS.6 The Cedergreen-Ritz-Streibig model

-- D --

daphnids Daphnia test
decontaminants Performance of decontaminants used in the culturing of a micro-organism
deguelin Deguelin applied to chrysanthemum aphis
drm Fitting dose-response models
drmc Sets control arguments

-- E --

earthworms Earthworm toxicity test
ED Estimating effective doses
ED.drc Estimating effective doses
EDcomp Comparison of relative potencies between dose-response curves
estfun.drc Bread and meat for the sandwich
etmotc Effect of erythromycin on mixed sewage microorganisms
EXD.2 Exponential decay model
EXD.3 Exponential decay model

-- F --

finney71 Example from Finney (1971)
fitted.drc Extract fitted values from model
FPL.4 Fractional polynomial-logistic dose-response models
fplogistic Fractional polynomial-logistic dose-response models

-- G --

G.2 Mean function for the Gompertz dose-response or growth curve
G.3 Mean function for the Gompertz dose-response or growth curve
G.3u Mean function for the Gompertz dose-response or growth curve
G.4 Mean function for the Gompertz dose-response or growth curve
G.aparine Herbicide applied to Galium aparine
gammadr Gamma dose-response model
gaussian Normal and log-normal biphasic dose-response models
genBliss Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
genBliss2 Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
genLoewe Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
genLoewe2 Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
genursa Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
germination Germination of three crops
getInitial Showing starting values used
getMeanFunctions Display available dose-response models
glymet Glyphosate and metsulfuron-methyl tested on algae.
gompertz Mean function for the Gompertz dose-response or growth curve
gompertzd The derivative of the Gompertz function

-- H --

H.virescens Mortality of tobacco budworms
hatvalues.drc Model diagnostics for nonlinear dose-response models
heartrate Heart rate baroreflexes for rabbits

-- I --

iceLoewe.1 Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
iceLoewe2.1 Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
isobole Creating isobolograms

-- L --

L.3 The logistic model
L.4 The logistic model
L.5 The logistic model
l2 The two-parameter log-logistic function
l3 The three-parameter log-logistic function
l3u The three-parameter log-logistic function
l4 The four-parameter log-logistic function
l5 The five-parameter log-logistic function
leaflength Leaf length of barley
lepidium Dose-response profile of degradation of agrochemical using lepidium
lettuce Hormesis in lettuce plants
lgaussian Normal and log-normal biphasic dose-response models
lin.test Lack-of-fit test for the mean structure based on cumulated residuals
LL.2 The two-parameter log-logistic function
LL.3 The three-parameter log-logistic function
LL.3u The three-parameter log-logistic function
LL.4 The four-parameter log-logistic function
LL.5 The five-parameter log-logistic function
LL2.2 The two-parameter log-logistic function
LL2.3 The three-parameter log-logistic function
LL2.3u The three-parameter log-logistic function
LL2.4 The four-parameter log-logistic function
LL2.5 The five-parameter log-logistic function
llogistic The log-logistic function
llogistic2 The log-logistic function
LN.2 Log-normal dose-response model
LN.3 Log-normal dose-response model
LN.3u Log-normal dose-response model
LN.4 Log-normal dose-response model
lnormal Log-normal dose-response model
logistic The logistic model
logLik.drc Extracting the log likelihood

-- M --

M.bahia Effect of an effluent on the growth of mysid shrimp
maED Estimation of ED values using model-averaging
MAX Maximum mean response
mecter Mechlorprop and terbythylazine tested on Lemna minor
metals Data from heavy metal mixture experiments
methionine Weight gain for different methionine sources
mixture Fitting binary mixture models
ml3a The Cedergreen-Ritz-Streibig model
ml3b The Cedergreen-Ritz-Streibig model
ml3c The Cedergreen-Ritz-Streibig model
ml4a Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
ml4b Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
ml4c Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
MM.2 Michaelis-Menten model
MM.3 Michaelis-Menten model
modelFit Assessing the model fit
mr.test Mizon-Richard test for dose-response models
mselect Dose-response model selection
multi2 Multistage dose-response model with quadratic terms

-- N --

nasturtium Dose-response profile of degradation of agrochemical using nasturtium
NEC Dose-response model for estimation of no effect concentration (NEC).
NEC.2 Dose-response model for estimation of no effect concentration (NEC).
NEC.3 Dose-response model for estimation of no effect concentration (NEC).
NEC.4 Dose-response model for estimation of no effect concentration (NEC).
neill.test Neill's lack-of-fit test for dose-response models
noEffect Testing if there is a dose effect at all

-- O --

O.mykiss Test data from a 21 day fish test

-- P --

P.promelas Effect of sodium pentachlorophenate on growth of fathead minnow
plot.drc Plotting fitted dose-response curves
plotFACI Calculation of combination index for binary mixtures
PR Expected or predicted response
predict.drc Prediction
predict.mrdrc Prediction
print.drc Printing key features
print.summary.drc Printing summary of non-linear model fits

-- R --

rdrm Simulating a dose-response curve
relpot Comparison of relative potencies between dose-response curves
residuals.drc Extracting residuals from the fitted dose-response model
RScompetition Competition between two biotypes
ryegrass Effect of ferulic acid on growth of ryegrass

-- S --

S.alba Potency of two herbicides
S.capricornutum Effect of cadmium on growth of green alga
searchdrc Searching through a range of initial parameter values to obtain convergence
secalonic Root length measurements
selenium Data from toxicology experiments with selenium
simDR Simulating ED values under various scenarios
spinach Inhibition of photosynthesis
summary.drc Summarising non-linear model fits

-- T --

terbuthylazin The effect of terbuthylazin on growth rate
twophase Two-phase dose-response model

-- U --

ucedergreen The Cedergreen-Ritz-Streibig model
UCRS.4a The Cedergreen-Ritz-Streibig model
UCRS.4b The Cedergreen-Ritz-Streibig model
UCRS.4c The Cedergreen-Ritz-Streibig model
UCRS.5a Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
UCRS.5b Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
UCRS.5c Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
uml3a The Cedergreen-Ritz-Streibig model
uml3b The Cedergreen-Ritz-Streibig model
uml3c The Cedergreen-Ritz-Streibig model
uml4a Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
uml4b Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
uml4c Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
update.drc Updating and re-fitting a model
ursa Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction

-- V --

vcov.drc Calculating variance-covariance matrix for objects of class 'drc'
vinclozolin Vinclozolin from AR in vitro assay

-- W --

W1.2 The two-parameter Weibull functions
W1.3 The three-parameter Weibull functions
W1.3u The three-parameter Weibull functions
W1.4 The four-parameter Weibull functions
w2 The two-parameter Weibull functions
W2.2 The two-parameter Weibull functions
W2.3 The three-parameter Weibull functions
W2.3u The three-parameter Weibull functions
W2.4 The four-parameter Weibull functions
W2x.3 The three-parameter Weibull functions
W2x.4 The four-parameter Weibull functions
w3 The three-parameter Weibull functions
w4 The four-parameter Weibull functions
weibull1 Weibull model functions
weibull2 Weibull model functions
weibull2x Weibull model functions

-- Y --

yieldLoss Calculating yield loss parameters