coxmeMlist {coxme} | R Documentation |
Coxme variance function
Description
This variance function accepts a list of matrices, which define a correlation structure for a coxme fit.
Usage
coxmeMlist(varlist, rescale = FALSE, pdcheck = TRUE, positive = TRUE)
Arguments
varlist |
a list containing one or more matrix or bdsmatrix objects. |
rescale |
if TRUE, each input matrix is rescaled to have a diagonal of 1. (Kinship matrices for instance are often generated with a diagonal of .5 and would be multiplied by 2). |
pdcheck |
check each matrix to ensure that it is positive definite |
positive |
constrain coefficients to be positive. This may also be a vector of
the same length as |
Details
If two matrices A
and B
were given, this fits
the variance structure
V= \sigma_1^2 A + \sigma_2^2 B
,
where the variances \sigma_1^2
and \sigma_2^2
are
parameters that will be optimized by coxme
,
treating A
and B
as fixed.
Value
a coxme variance family object, used by coxme
in the fitting process.
Author(s)
Terry Therneau