Centered Isotonic Regression and Dose-Response Utilities

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Documentation for package ‘cir’ version 2.3.1

• DESCRIPTION file.
• User guides, package vignettes and other documentation.

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agcouCI	Standard unordered-Binomial confidence interval utilities.
cir	Isotonic Regression, Centered Isotonic Regression, and Dose-Response Utilities
cirPAVA	Returns centered-isotonic-regression estimate
deltaInverse	Calculate inverse (dose-finding) intervals, using local inversion and the Delta method
doseFind	Inverse (dose-finding) estimate of a target x value (e.g., a percentile)
doseResponse	Constructor functions and class-checking functions for DRtrace and doseResponse classes
DRshrink	Shrinkage fix to bias in observed rates under adaptive dose-finding design
DRtrace	Constructor functions and class-checking functions for DRtrace and doseResponse classes
is.doseResponse	Constructor functions and class-checking functions for DRtrace and doseResponse classes
is.DRtrace	Constructor functions and class-checking functions for DRtrace and doseResponse classes
isotInterval	Returns analytical interval estimates, given isotonic-regression (centered or not) point estimates
iterCIR	Centered-isotonic-regression (CIR): iterative version for better bias correction
jeffCI	Standard unordered-Binomial confidence interval utilities.
morrisCI	Analytical confidence intervals using the Morris (1988) algorithm
oldPAVA	Returns standard isotonic-regression estimate, with flexible dose-response input
plot.doseResponse	Plotting Methods for DRtrace, doseResponse Objects
plot.DRtrace	Plotting Methods for DRtrace, doseResponse Objects
quickInverse	Point and Interval Inverse Estimation ("Dose-Finding"), using CIR and IR
quickIsotone	One-Stop-shop Forward point and interval estimation via CIR or IR
slope	Piecewise-linear local slopes given a (non-strictly) monotone x-y sequence
wilsonCI	Standard unordered-Binomial confidence interval utilities.