| braidReports-package {braidReports} | R Documentation |
Visualize Combined Action Response Surfaces and Report BRAID Analyses
Description
Building on the ggplot2 plotting package, this package provides functions to generate,
format, and style surface plots for visualizing combined action data without resorting to
three-dimensional surface plots, which can be difficult to interpret. The package also provides
functions for reporting on a BRAID analysis, including plotting curve-shifts, calculating IAE
values, and producing full BRAID analysis reports.
Details
| Package: | braidReports |
| Type: | Package |
| Version: | 0.5.3 |
| Date: | 2016-04-05 |
| License: | GPL (>=3) |
The heart of the package is the function responseMap, which produces a ggplot2
tile or surface plot from combined action data, consolidating many of the minutiae of plotting such
surfaces into a single, easily used function. The functions formatResponseMap and
formatDifferenceMap provide pre-built formatting and themes for quickly generating
publishable or shareable activity plots and error plots. In addition, several functions provide
additional analytical and reporting options for BRAID analyses (from the package braidrm).
The function calculateIAE estimates the combined therapeutic window for a pair of
active compounds; the function potentiationPlot produces fast and easy curve-shift
plots to visualize the potentiation of one compound by the presence of another; and
makeBRAIDreport serves as a (nearly) fully-functional apparatus for translating
a BRAID analysis into a one-page comprehensive report.
Author(s)
Nathaniel R. Twarog <nathaniel.twarog@stjude.org>
References
Twarog, N.R., Stewart, E., Vowell Hamill, C., and Shelat, A. BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action. Scientific Reports In Press (2016).