historical_survival {bayesCT} | R Documentation |

Wrapper function for historical data from time-to-event outcome.

historical_survival( time = NULL, treatment = NULL, event = NULL, discount_function = "identity", alpha_max = 1, fix_alpha = FALSE, weibull_scale = 0.135, weibull_shape = 3, method = "fixed", .data = NULL )

`time` |
vector. exposure time for the subjects. It must be the same length as the treatment variable. |

`treatment` |
vector. treatment assignment for patients, 1 for treatment group and 0 for control group |

`event` |
vector. The status indicator, normally 0=alive, 1=dead. Other choices are TRUE/FALSE (TRUE = death) or 1/2 (2=death). For censored data, the status indicator is 0=right censored, 1 = event at time. Although unusual, the event indicator can be omitted, in which case all subjects are assumed to have an event. |

`discount_function` |
character. If incorporating historical data, specify
the discount function. Currently supports the Weibull function
( |

`alpha_max` |
scalar. Maximum weight the discount function can apply. Default is 1. For a two-arm trial, users may specify a vector of two values where the first value is used to weight the historical treatment group and the second value is used to weight the historical control group. |

`fix_alpha` |
logical. Fix alpha at alpha_max? Default value is FALSE. |

`weibull_scale` |
scalar. Scale parameter of the Weibull discount function used to compute alpha, the weight parameter of the historical data. Default value is 0.135. For a two-arm trial, users may specify a vector of two values where the first value is used to estimate the weight of the historical treatment group and the second value is used to estimate the weight of the historical control group. Not used when discount_function = "identity". |

`weibull_shape` |
scalar. Shape parameter of the Weibull discount function used to compute alpha, the weight parameter of the historical data. Default value is 3. For a two-arm trial, users may specify a vector of two values where the first value is used to estimate the weight of the historical treatment group and the second value is used to estimate the weight of the historical control group. Not used when discount_function = "identity". |

`method` |
character. Analysis method with respect to estimation of the weight
paramter alpha. Default method " |

`.data` |
NULL. stores the historical time, treatment and event , please do not fill it in. |

a list with historical data for time-to-event outcome with the discount function.

historical_survival(time = rexp(10, 0.01), treatment = rep(10, 1), event = rep(10, 1))

[Package *bayesCT* version 0.99.3 Index]