pow {baskexact}  R Documentation 
Power
Description
Computes the exact power for a basket trial.
Usage
pow(design, ...)
## S4 method for signature 'OneStageBasket'
pow(
design,
p1,
n,
lambda,
weight_fun,
weight_params = list(),
globalweight_fun = NULL,
globalweight_params = list(),
results = c("ewp", "group"),
...
)
## S4 method for signature 'TwoStageBasket'
pow(
design,
p1,
n,
n1,
lambda,
interim_fun,
interim_params = list(),
weight_fun,
weight_params = list(),
globalweight_fun = NULL,
globalweight_params = list(),
results = c("ewp", "group"),
...
)
Arguments
design 
An object of class 
... 
Further arguments. 
p1 
Probabilities under the alternative hypothesis. If

n 
The sample size per basket. 
lambda 
The posterior probability threshold. See details for more information. 
weight_fun 
Which function should be used to calculate the pairwise weights. 
weight_params 
A list of tuning parameters specific to

globalweight_fun 
Which function should be used to calculate the global weights. 
globalweight_params 
A list of tuning parameters specific to

results 
Whether only the experimentwise power (option 
n1 
The sample size per basket for the interim analysis in case of a twostage design. 
interim_fun 
Which type of interim analysis should be conducted in case of a twostage design. 
interim_params 
A list of tuning parameters specific to

Details
pow
computes the exact experimentwise power and the
exact rejection probabilities per group. The experimentwise power
is the probability to reject at least one null hypothesis for a basket with
p1 > p0. The rejection probabilities correspond to the type 1 error
rate for baskets with p1 = p0 and to the power for baskets with
p1 > p0.
If prune = TRUE
then the baskets with an observed number of baskets
smaller than the pooled critical value are not borrowed from. The
pooled critical value is the smallest integer c for which all null
hypotheses can be rejected if the number of responses is exactly c for
all baskets.
This method is implemented for the class OneStageBasket
.
Value
If results = "ewp"
then the experimentwise power is
returned as a numeric value. If results = "group"
then a list with
the rejection probabilities per group and the experimentwise power
is returned. For baskets with p1 = p0 the rejection probabilities
corresponds to the type 1 error rate, for baskets with p1 > p0 the
rejection probabilities corresponds to the power.
Methods (by class)

pow(OneStageBasket)
: Power for a singlestage basket design. 
pow(TwoStageBasket)
: Power for a twostage basket design.
Examples
design < setupOneStageBasket(k = 3, p0 = 0.2)
pow(design, p1 = c(0.2, 0.5, 0.5), n = 15, lambda = 0.99,
weight_fun = weights_fujikawa, weight_params = list(epsilon = 2, tau = 0))