ahazpen.pen.control {ahaz} R Documentation

## Penalty controls for ahazpen

### Description

Describe the penalty function to be used in the penalized semiparametric additive hazards model. Typically only used in a call to ahazpen or tune.ahazpen.

### Usage

# (Adaptive) lasso/elasticnet



### Arguments

 alpha Elasticnet penalty parameter with default alpha=1 corresponding to the standard lasso; see details. ada.wgt Optional covariate weights used for fitting the adaptive lasso. Default is not to use weights, i.e. fit the standard lasso. A user-specified init.sol can be a nonnegative vector of length corresponding to the number of covariates in the model. For advanced use it may also be specified as a function with arguments surv, X and weights precisely; see the details. a Parameter of the stepwise SCAD penalty, see details. Default is a=3.7 nsteps Number of steps in stepwise SCAD. Default is nsteps=1. init.sol Optional initial solution for stepwise SCAD consisting of a numerical vector of length corresponding to the number of covariates in the model. Default is a vector of regression coefficients obtained from ahaz if there are more observations than covariates, zero otherwise. For advanced use, initsol it can also be specified as a function with arguments surv, X and weights precisely; see the details. c Optional scaling factor for stepwise SCAD. Usually it is not necessary to change supply this; see the details.

### Details

The lasso/elasticnet penalty function takes the form

p_\lambda(\beta)=\lambda((1-\alpha)\|\beta\|_2 + \alpha\|\beta\|_1)

where 0 <\alpha \leq 1. Choosing \alpha<1 encourages joint selection of correlated covariates and may improve the fit when there are substantial correlations among covariates.

The stepwise SCAD penalty function takes the form

 p_\lambda(\beta)=w_\lambda(c|b_1|)|\beta_1|+\ldots+ w_\lambda(c|b_{nvars}|)|\beta_{nvars}|

where b is some initial estimate, c is a scaling factor, and for I the indicator function

w_\lambda(x)=\lambda I(x \le \lambda) + \frac{(a\lambda - x)_+}{a - 1}I(x>\lambda)

The scaling factor c controls how ‘different’ the stepwise SCAD penalty is from the standard lasso penalty (and is also used to remove dependency of the penalty on the scaling of the time axis).

The one-step SCAD method of Zou & Li (2008) corresponds to taking b equal to the estimator derived from ahaz. See Gorst-Rasmussen & Scheike (2011) for details. By iterating such one-step SCAD and updating the initial solution b accordingly, the algorithm approximates the solution obtained using full SCAD. Note that calculating the full SCAD solution generally leads to a nonconvex optimization problem: multiple solutions and erratic behavior of solution paths can be an issue.

The arguments ada.wgt and init.sol can be specified as functions of the observations. This is convenient, for example, when using cross-validation for tuning parameter selection. Such a function must be specified precisely with the arguments surv, X and weights and must output a numeric vector of length corresponding to the number of covariates. ahazpen will take care of scaling so the function should produce output on the original scale. See the examples here as well as the examples for tune.ahazpen for usage of this feature in practice.

### Value

An object with S3 class "ahaz.pen.control".

 type Type of penalty. init.sol Function specifying the initial solution, if applicable. alpha Value of alpha, if applicable. nsteps Number of steps for stepwise SCAD penalty, if applicable. a Parameter for stepwise SCAD penalty, if applicable. c Scaling factor for stepwise SCAD penalty, if applicable. ada.wgt Function specifying the weights for the adaptive lasso penalty, if applicable.

### References

Gorst-Rasmussen, A. & Scheike, T. H. (2011). Independent screening for single-index hazard rate models with ultra-high dimensional features. Technical report R-2011-06, Department of Mathematical Sciences, Aalborg University.

Leng, C. & Ma, S. (2007). Path consistent model selection in additive risk model via Lasso. Statistics in Medicine; 26:3753-3770.

Martinussen, T. & Scheike, T. H. (2008). Covariate selection for the semiparametric additive risk model. Scandinavian Journal of Statistics; 36:602-619.

Zou, H. & Li, R. (2008). One-step sparse estimates in nonconcave penalized likelihood models, Annals of Statistics; 36:1509-1533.

ahazpen, tune.ahazpen

### Examples

data(sorlie)

# Break ties
set.seed(10101)
time <- sorlie$time+runif(nrow(sorlie))*1e-2 # Survival data + covariates surv <- Surv(time,sorlie$status)
X <- as.matrix(sorlie[,3:ncol(sorlie)])

# Fit additive hazards regression model with elasticnet penalty
model <- ahazpen(surv,X,penalty=lasso.control(alpha=0.1),dfmax=30)
plot(model)

# Adaptive lasso with weights 1/|beta_i|^0.5. Note that, although
# we do not use 'weights', it MUST be included as an argument
return(1/abs(coef(ahaz(surv,X)))^.5)
plot(model)

# One-step SCAD with initial solution derived from univariate regressions
fit <- ahaz(surv,X,univariate=TRUE)
return(coef(fit))
}
set.seed(10101)
plot(model.ssc)


[Package ahaz version 1.15 Index]