TwoStageDesign-class {adestr}

Re-export of two-stage design class

Description

This is a re-export of the TwoStageDesign class from the adoptr (Kunzmann et al. 2021) package.

Details

This function is currently re-exported here to resolve CRAN conflicts. For details, please refer to the paper (Kunzmann et al. 2021) and the original github repository https://github.com/kkmann/adoptr.

Slots

n1

(numeric) first-stage sample size.

c1f

(numeric) first-stage futility boundary.

c1e

(numeric) first-stage early efficacy boundary.

n2_pivots

(numeric) vector containing the values of the n2 spline function.

c2_pivots

(numeric) vector containing the values of the second-stage rejection boundary spline c2

x1_norm_pivots

(numeric) vector containing the x-axis (z-sclae) points for the n2 and c2 splines

weights

(numeric) vector containing integration weights

tunable

(logical) vector determining whether desing paramters are to be optimized

See Also

The original implementation of the adoptr package by Kevin Kunzmann and Maximilian Pilz is available at https://github.com/kkmann/adoptr.