KdA {VDAP}

Peptide Dissociation Rate Constant (Kd) Calculations

Description

Calculates the Kd of each peptide using a non-linear single site specific binding model. A sub-function of vFormat

Usage

KdA(x, y, z)

Arguments

x

An R object, generally a data.frame, containing peptides in the first column

y

The concentrations of each column used for Kd calculations, separated by commas. The order must match the relative position of the columns.

z

The columns used for Kd calculations, expressed as a sequence. Ex: Columns 2 through 4 = 2:4

Note

Uses the R package: drc created by Christian Ritz and Jens C. Strebig

Author(s)

Cody Moore

Examples

protEx <- data.frame(Peptides = c("PWRGPWARVGSG","GYNRVGQGSG","PWRGPWARVGSG"),
C_6uM = c(65011.48,47462.24,24778), C_3uM = c(62637.81,31899.85,21313.67),
C_1.5uM = c(57893.22,25911.35,10397.99))

exKdA <- KdA(protEx,c(6,3,1.5),2:4)