QOL {TrialSize}

Quality of life

Description

Under the time series model, determine sample size based on normal approximation.

Usage

QOL(alpha, beta, c, epsilon)

Arguments

alpha

significance level

beta

power = 1-beta

c

constant c=0.5

epsilon

a meaningful difference epsilon. If the chosen acceptable limits are (-\delta, \delta). epsilon=\delta-\eta, \eta is the measure for detecting an equivalence when the true difference in treatment means is less than a small constant \eta.

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

Example.15.4.3<-QOL(0.05,0.1,0.5,0.25)
Example.15.4.3