ISCV.Equivalence {TrialSize}

Test for Equivalence of Intra-Subject CVs

Description

H0: |CVr - CVt| \ge \delta

Ha: |CVr - CVt| < \delta

Usage

ISCV.Equivalence(alpha, beta, CVt, CVr, m, margin)

Arguments

alpha

significance level

beta

power = 1-beta

CVt

Coefficient Of Variation for treatment T

CVr

Coefficient Of Variation for treatment R

m

for each subject, there are m replicates.

margin

margin=delta,

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003