Estimation of the Proportion of Treatment Effect Explained by Surrogate Outcome Information


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Documentation for package ‘SurrogateOutcome’ version 1.1

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SurrogateOutcome-package Estimation of the Proportion of Treatment Effect Explained by Surrogate Outcome Information
delta.estimate Estimates the treatment effect at time t, defined as the difference in the restricted mean survival time
delta.q.event.RMST Calculates the residual treatment effect (the difference in restricted mean survival time at time t) after accounting for the treatment effect on the surrogate outcome information up to the landmark time
delta.q.event.semi.RMST Calculates the residual treatment effect (the difference in restricted mean survival time at time t) after accounting for the treatment effect on the surrogate outcome information up to the landmark time
delta.t.RMST Calculates the residual treatment effect (the difference in restricted mean survival time at time t) after accounting for the treatment effect on the primary outcome up to the landmark time
ExampleData Hypothetical data
IV.event Calculates the incremental value of the surrogate outcome information
R.q.event Calculates the proportion of the treatment effect (the difference in restriced mean survival time at time t) explained by surrogate outcome information observed up to the landmark time
R.t.estimate Calculates the proportion of the treatment effect (the difference in restricted mean survival time at time t) explained by primary outcome information observed up to the landmark time
SurrogateOutcome Estimation of the Proportion of Treatment Effect Explained by Surrogate Outcome Information