getLncGenePairs {SubpathwayLNCE} | R Documentation |
Get the co-express lncRNA-mRNA interactions
Description
Get the co-express lncRNA-mRNA interactions reached a significant positive threshold. These lncRNAs-mRNAs pairs are competitivly rugulated.
Usage
getLncGenePairs(GeneExp,LncExp,a=0.025)
Arguments
GeneExp |
A gene expression profile. The first row of gene expression profile is names of mRNA, and the gene expression profile and the lncRNA expression profile must be mached. |
LncExp |
A lncRNA expression profile. The first row of lncRNA expression profile is names of lncRNA, and the gene expression profile and the lncRNA expression profile must be mached. |
a |
A parameter,namely the significant positive threshold. |
Details
Co-express coefficient for any pair of relations in the candidate LncRNA-mRNA network is calculated basing on matched LncRNA and mRNA expression profiles, those relations had reached a significant positive threshold were retained.
Value
A data frame. The data frame has two columns, the fist is lncRNA names, the other is mRNA names.
Author(s)
Xinrui Shi, Chunquan Li and Xia Li
Examples
## Not run:
GeneExp<-GetExampleData(exampleData="GeneExp")
LncExp<-GetExampleData(exampleData="LncExp")
LncGenePairs<-getLncGenePairs(GeneExp,LncExp,a=0.025)
## End(Not run)