SITH-package |
Visualize and analyze intratumor heterogeneity using a spatial model of tumor growth |
bulkSample |
Simulate bulk sampling |
plotSlice |
2D cross section of the simulated tumor |
progressionChain |
Create a linear chain graph to describe the order of mutations |
progressionDAG_from_igraph |
Define the progression of mutations from an 'igraph' object |
randomBulkSamples |
Simulate multi-region bulk sampling |
randomNeedles |
Simulate fine needle aspiration |
randomSingleCells |
Simulate single cell sequencing data |
simulateTumor |
Spatial simulation of tumor growth |
singleCell |
Simulate single cell sequencing data |
SITH |
Visualize and analyze intratumor heterogeneity using a spatial model of tumor growth |
spatialDistribution |
Quantify the spatial distribution of mutants |
visualizeTumor |
Interactive visualization of the simulated tumor |