A Spatial Model of Intra-Tumor Heterogeneity
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Documentation for package ‘SITH’ version 1.1.0
Help Pages
| SITH-package | Visualize and analyze intratumor heterogeneity using a spatial model of tumor growth |
| bulkSample | Simulate bulk sampling |
| plotSlice | 2D cross section of the simulated tumor |
| progressionChain | Create a linear chain graph to describe the order of mutations |
| progressionDAG_from_igraph | Define the progression of mutations from an 'igraph' object |
| randomBulkSamples | Simulate multi-region bulk sampling |
| randomNeedles | Simulate fine needle aspiration |
| randomSingleCells | Simulate single cell sequencing data |
| simulateTumor | Spatial simulation of tumor growth |
| singleCell | Simulate single cell sequencing data |
| SITH | Visualize and analyze intratumor heterogeneity using a spatial model of tumor growth |
| spatialDistribution | Quantify the spatial distribution of mutants |
| visualizeTumor | Interactive visualization of the simulated tumor |