simu_cluster {SCRIP}

SCRIP simulation for clustering analysis with multiple cell types

Description

Simulate count data for clustering analysis by preserving variably expressed genes with multiple cell types

Usage

simu_cluster(expre_data, pheno_data, CTlist, mode, nfeatures, seed = 2021)

Arguments

expre_data

data matrix required for simulation

pheno_data

phenotype data information

CTlist

cell types used for simulation

mode

"GP-commonBCV", "BP-commonBCV", "BP", "BGP-commonBCV" and "BGP-trendedBCV"

nfeatures

parameter required for FinalVariable function in Seurat package

seed

seed used for simulation

Value

simulated read counts data with cell type information