SCRIPsimBCVMeans {SCRIP}

Simulate BCV means

Description

Simulate means for each gene in each cell that are adjusted to follow a mean-variance trend using Biological Coefficient of Variation taken from and inverse gamma distribution.

Usage

SCRIPsimBCVMeans(data, sim, params)

Arguments

data

data are used to fit the mean-BCV trend for simulation

sim

SingleCellExperiment to add BCV means to.

params

SplatParams object with simulation parameters.

Value

SingleCellExperiment with simulated BCV means.