| Kryukov {Ravages} | R Documentation |
Kryukov data set
Description
The data from Kryukov et al, 2009, contain simulated site frequency spectrum data using European demographic models with purifying selection.
Usage
data(Kryukov) Format
Kryukov is a dataframe with four columns:
- gene
The unit of each variant
- maf
The maf of each variant in the European population
- selection.coefficient
The selction coefficient of each variant in the European population
- position
The position of each variant
Details
200 units are present corresponding to 200 genes. For each unit, the data set contains the maf in the European population, the selection coefficient and the position of each variant.
Source
The data were obtained from the SeqPower software (see also http://www.bioinformatics.org/spower/input#data_download).
References
Kryukov et al, 2009, Power of deep, all-exon resequencing for discovery of human trait genes, Proceedings of the National Academy of Sciences, DOI:10.1073/pnas.0812824106