QGglmm-package {QGglmm} | R Documentation |
Estimate Quantitative Genetics Parameters from Generalised Linear Mixed Models
Description
Compute various quantitative genetics parameters from a Generalised Linear Mixed Model (GLMM) estimates. Especially, it yields the observed phenotypic mean, phenotypic variance and additive genetic variance.
Details
The DESCRIPTION file:
Package: | QGglmm |
Type: | Package |
Title: | Estimate Quantitative Genetics Parameters from Generalised Linear Mixed Models |
Version: | 0.7.4 |
Date: | 2020-01-03 |
Author: | Pierre de Villemereuil <bonamy@horus.ens.fr> |
Maintainer: | Pierre de Villemereuil <bonamy@horus.ens.fr> |
BugReports: | https://github.com/devillemereuil/qgglmm/issues |
Description: | Compute various quantitative genetics parameters from a Generalised Linear Mixed Model (GLMM) estimates. Especially, it yields the observed phenotypic mean, phenotypic variance and additive genetic variance. |
Imports: | cubature (>= 1.4) |
License: | GPL-2 |
Index of help topics:
QGglmm-package Estimate Quantitative Genetics Parameters from Generalised Linear Mixed Models QGicc Intra - Class Correlation coefficients (ICC) on the observed data scale QGlink.funcs List of functions according to a distribution and a link function QGmean Compute the phenotypic mean on the observed scale QGmvicc Intra - Class Correlation coefficients (ICC) on the observed data scale (multivariate analysis). QGmvmean Compute the multivariate phenotypic mean on the observed scale QGmvparams Quantitative Genetics parameters from GLMM estimates (multivariate analysis). QGmvpred Predict the evolutionary response to selection on the observed scale QGmvpsi Compute a multivariate "Psi" (used to compute the additive genetic variance on the observed scale). QGparams Quantitative Genetics parameters from GLMM estimates. QGpred Predict the evolutionary response to selection on the observed scale QGpsi Compute "Psi" (used to compute the additive genetic variance on the observed scale). QGvar.dist Compute the distribution variance QGvar.exp Compute the variance of expected values (i.e. the latent values after inverse-link transformation.) QGvcov Compute the phenotypic variance-covariance matrix on the observed / expected scale
This package gives the values on the observed scale for several quantitative genetics parameter using estimates from a Generalised Linear Mixed Model (GLMM). If a fitness function is assumed or measured, it also predicts the evolutionary response to selection on the observed scale.
The two main functions of this package are QGparams
and QGpred
. The first allows to compute the quantitative genetics parameters on the observed scale for any given GLMM and its estimates. The second allows to compute a predicted response to evolution on the observed scale using GLMM estimates and an assumed/measured/inferred fitness function.
For some distribution/link models (e.g. Binomial/probit and Poisson and Negative Binomial with logartihm or square-root link), a closed form solutions of the integrals computed by this package are available. They are automatially used by QGparams
and this function only.
Author(s)
Pierre de Villemereuil <bonamy@horus.ens.fr>
Maintainer: Pierre de Villemereuil <bonamy@horus.ens.fr>
References
de Villemereuil, P., Schielzeth, H., Nakagawa, S., and Morrissey, M.B. (2016). General methods for evolutionary quantitative genetic inference from generalised mixed models. Genetics 204, 1281-1294.