Optimal Two-Period Multiarm Platform Design with New Experimental Arms Added During the Trial


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Documentation for package ‘PlatformDesign’ version 2.1.4

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admiss Find the admissible set in a two-period K+M-experimental arm platform design with delayed arms
cor.mat Calculate the correlation matrix of the z-statistics for a two-period K+M-experimental arm platform design with delayed arms
fwer_critical Calculate the critical value and the marginal type-I error rate
one_design Calculate other design parameters of a two-period K+M-experimental arm platform design given sample sizes
one_stage_multiarm Calculate the sample sizes and other design parameters for an one-stage K-experimental arm trial using the root-K rule for the allocation ratio, controlling for FWER or PWER
platform_design Design an optimal two-period multiarm platform trial with new experimental arms added during the trial, controlling for FWER or PWER
platform_design2 A faster version of platform_design()