chackoTest {PMCMRplus}R Documentation

Testing against Ordered Alternatives (Chacko's Test)

Description

Performs Chacko's test for testing against ordered alternatives.

Usage

chackoTest(x, ...)

## Default S3 method:
chackoTest(x, g, alternative = c("greater", "less"), ...)

## S3 method for class 'formula'
chackoTest(formula, data, subset, na.action, alternative = alternative, ...)

Arguments

x

a numeric vector of data values, or a list of numeric data vectors.

...

further arguments to be passed to or from methods.

g

a vector or factor object giving the group for the corresponding elements of "x". Ignored with a warning if "x" is a list.

alternative

the alternative hypothesis. Defaults to greater.

formula

a formula of the form response ~ group where response gives the data values and group a vector or factor of the corresponding groups.

data

an optional matrix or data frame (or similar: see model.frame) containing the variables in the formula formula. By default the variables are taken from environment(formula).

subset

an optional vector specifying a subset of observations to be used.

na.action

a function which indicates what should happen when the data contain NAs. Defaults to getOption("na.action").

Details

The null hypothesis, H_0: \theta_1 = \theta_2 = \ldots = \theta_k is tested against a simple order hypothesis, H_\mathrm{A}: \theta_1 \le \theta_2 \le \ldots \le \theta_k,~\theta_1 < \theta_k.

Let R_{ij} be the rank of X_{ij}, where X_{ij} is jointly ranked from \left\{1, 2, \ldots, N \right\}, ~~ N = \sum_{i=1}^k n_i, then the test statistic is calculated as

H = \frac{1}{\sigma_R^2} \sum_{i=1}^k n_i \left(\bar{R^*}_i - \bar{R}\right),

where \bar{R^*}_i is the isotonic mean of the i-th group and \sigma_R^2 = N \left(N + 1\right) / 12 the expected variance (without ties). H_0 is rejected, if H > \chi^2_{v,\alpha} with v = k -1 degree of freedom. The p-values are estimated from the chi-square distribution.

Value

A list with class "htest" containing the following components:

method

a character string indicating what type of test was performed.

data.name

a character string giving the name(s) of the data.

statistic

the estimated quantile of the test statistic.

p.value

the p-value for the test.

parameter

the parameters of the test statistic, if any.

alternative

a character string describing the alternative hypothesis.

estimates

the estimates, if any.

null.value

the estimate under the null hypothesis, if any.

Source

The source code for the application of the pool adjacent violators theorem to calculate the isotonic means was taken from the file "pava.f", which is included in the package Iso:

Rolf Turner (2015). Iso: Functions to Perform Isotonic Regression. R package version 0.0-17. https://CRAN.R-project.org/package=Iso.

The file "pava.f" is a Ratfor modification of Algorithm AS 206.1:

Bril, G., Dykstra, R., Pillers, C., Robertson, T. (1984) Statistical Algorithms: Algorithm AS 206: Isotonic Regression in Two Independent Variables, Appl Statist 34, 352–357.

The Algorith AS 206 is available from StatLib http://lib.stat.cmu.edu/apstat/. The Royal Statistical Society holds the copyright to these routines, but has given its permission for their distribution provided that no fee is charged.

Note

Factor labels for g must be assigned in such a way, that they can be increasingly ordered from zero-dose control to the highest dose level, e.g. integers {0, 1, 2, ..., k} or letters {a, b, c, ...}. Otherwise the function may not select the correct values for intended zero-dose control.

It is safer, to i) label the factor levels as given above, and to ii) sort the data according to increasing dose-levels prior to call the function (see order, factor).

The function does neither check nor correct for ties.

References

Chacko, V. J. (1963) Testing homogeneity against ordered alternatives, Ann Math Statist 34, 945–956.

See Also

kruskalTest and shirleyWilliamsTest of the package PMCMRplus, kruskal.test of the library stats.

Examples

## Example from Sachs (1997, p. 402)
x <- c(106, 114, 116, 127, 145,
       110, 125, 143, 148, 151,
       136, 139, 149, 160, 174)
g <- gl(3,5)
levels(g) <- c("A", "B", "C")

## Chacko's test
chackoTest(x, g)

## Cuzick's test
cuzickTest(x, g)

## Johnson-Mehrotra test
johnsonTest(x, g)

## Jonckheere-Terpstra test
jonckheereTest(x, g)

## Le's test
leTest(x, g)

## Spearman type test
spearmanTest(x, g)

## Murakami's BWS trend test
bwsTrendTest(x, g)

## Fligner-Wolfe test
flignerWolfeTest(x, g)

## Shan-Young-Kang test
shanTest(x, g)


[Package PMCMRplus version 1.9.10 Index]