process_drug_target_interactions {PANACEA}

Process Drug-Target Interactions

Description

Process Drug-Target Interactions

Usage

process_drug_target_interactions(
  drug_target_interactions,
  PIN_genes,
  drug_name_col = "drug_name",
  target_col = "gene_name"
)

Arguments

drug_target_interactions

data frame containing drugs and target genes

PIN_genes

gene symbols for the chosen PIN

drug_name_col

name of the column containing drug names (default = "drug_name")

target_col

name of the column containing drug targets (default = "converted_target_gene")

Value

processed drug-target interactions. Processing involves converting symbols missing in the PIN, merging drugs that have the same target gene(s)