d11 {Opt5PL}

Computing each element of the function DD_weight_1

Description

This function computes each element of the vector function DD_weight_1 which is the first derivative of the Ds-optimality criterion with respect to the model parameters.

Usage

d11(T, x, xl, inv, inv1, order)

Arguments

T

A numeric vector. Model parameter values

x

A numeric. ith dose level for a given design

xl

A numeric. last dose level for a given design

inv

A numeric matrix. Inverse of the information matrix for the 5PL model

inv1

A numeric matrix. Inverse of the information matrix for the 4PL model

order

numeric. The number of model paraemters