Nominating Quality Control Outliers in Genomic Profiling Studies


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Documentation for package ‘OmicsQC’ version 1.1.0

Help Pages

accumulate.zscores Sum across sign corrected z-scores for total sample quality score
correct.zscore.signs Corrects the z-scores signs according to the metrics
cosine.similarity.cutoff Calculate an outlier cutoff using cosine similarity
cosine.similarity.iterative Tests the accumulated quality scores for outliers using cosine similarity
example.qc.dataframe QC metrics across 100 samples
fit.and.evaluate Fits the QC data to distributions and returns the KS test result and BIC score
get.qc.barplot Generates the standard barplot of scores for each sample
get.qc.heatmap Generates the standard heatmap of scores for each sample.
get.qc.multipanelplot Generates the multipanel plot of heatmap and barplot
sign.correction Directionality of QC metrics
ylabels Formatted QC metrics labels
zscores.from.metrics Calculate z-scores for each metric across each sample