olink_lod {OlinkAnalyze}

Calculate LOD using Negative Controls or Fixed LOD

Description

Calculate LOD using Negative Controls or Fixed LOD

Usage

olink_lod(data, lod_file_path = NULL, lod_method = "NCLOD")

Arguments

data

npx data file

lod_file_path

location of lod file from Olink. Only needed if lod_method = "FixedLOD". Default 'NULL'.

lod_method

method for calculating LOD using either "FixedLOD" or negative controls ("NCLOD"). Default 'NCLOD'.

Value

A dataframe with 2 additional columns, LOD and PCNormalizedLOD. When 'Normalization = "Plate Control"', LOD and PCNormalizedLOD are identical.

Examples

## Not run: 
   \donttest{
  try({ # This will fail if the files do not exist.

  # Import NPX data
    npx_data <- read_NPX("path/to/npx_file")

  # Estimate LOD from negative controls
    npx_data_lod_NC <- olink_lod(data = npx_data,  lod_method = "NCLOD")

  # Estimate LOD from fixed LOD
  ## Locate the fixed LOD file
    lod_file_path <- "path/to/lod_file"

    npx_data_lod_Fixed <- olink_lod(data = npx_data,
                                    lod_file_path = lod_file_path,
                                    lod_method = "FixedLOD")
     })
  }

## End(Not run)