drugComb {NIMAA}

drugComb

Description

DrugComb is a web-based portal for storing and analyzing drug combination screening datasets, containing 739,964 drug combination experiments across 2320 cancer cell lines and 8397 drugs. Single drug screening was extracted and provided here as a subset of drug combination experiments.

Usage

drugComb

Format

A tibble with three variables:

inhibitor

names of inhibitors

cell_line

cell_line for each inhibitor

median

the median of drug response at corresponding inhibitor and cell_line

Source

Zheng, S., Aldahdooh, J., Shadbahr, T., Wang, Y., Aldahdooh, D., Bao, J., Wang, W., Tang, J. (2021). DrugComb update: a more comprehensive drug sensitivity data repository and analysis portal, Nucleic Acids Research, 49(W1), W174–W184. https://academic.oup.com/nar/article/49/W1/W174/6290546