Corrp2miRfile {MiRSEA} | R Documentation |
create a pathway-microRNA(miRNA) profile and a p value matrix
Description
The function Corrp2miRfile
create a p value matrix and a pathway-miRNA correlation profile
Usage
Corrp2miRfile(pathway="kegg", species = "hsa")
Arguments
pathway |
choose database of pathway,"kegg","biocarta" or"reactome" |
species |
Species of miRNAs(default: hsa) |
Details
When users input interesting species and pathway, the function can calculate the p value between pathway and miRNA using hypergeometric.The p value can quantify the strength of the pathway regulated by each miRNA.The smaller p value is represent the bigger strength of regulate.Then p2m can get miRNA set(pmSET)for each pathway,which is a co-regulated miRNA set of this pathway(w>0).
Value
p |
A p value weighted matrix (rows are pathway ,cols are miRNAs) |
p2miR |
pathway-miRNA correlation(pmSET) profile |
Author(s)
Junwei Hanhanjunwei1981@163.com,Siyao Liu liusiyao29@163.com
References
Rivals I, Personnaz L, Taing L, & Potier MC (2007) Enrichment or depletion of a GO category within a class of genes: which test? (Translated from eng) Bioinformatics 23(4):401-407 (in eng).
See Also
Examples
## Not run:
p2m<-Corrp2miRfile(pathway="kegg", species = "example")
p2m$p[1,1:10]
p2m$p2miR[1,1:5]
## End(Not run)