inner.CSKAT {MiRKAT}

Inner Function for CSKAT, Correlated Sequence Kernel Association Test

Description

Small-sample SKAT for correlated (continuous) data ('c' stands for 'correlated'). Computes the adjusted score statistic and p-value.

Usage

inner.CSKAT(lmer.obj, K)

Arguments

lmer.obj

A fitted lme4 object (model under H0)

K

the kernel matrix, which quantifies the similarities between samples

Value

p.value

association p-value

Q.adj

adjusted score statistic

References

Zhan X, et al. (2018) A small-sample kernel association test for correlated data with application to microbiome association studies. Genet Epidemiol., submitted.