MVcML_SdTheta {MendelianRandomization} | R Documentation |
Standard error estimate for MVMR-cML-BIC
Description
This is based on the profile likelihood of the set of valid IVs, which is not robust to uncertainty in model selection.
Usage
MVcML_SdTheta(b_exp, b_out, Sig_inv_l, theta, zero_ind, r_vec = NULL)
Arguments
b_exp |
A matrix of SNP effects on the exposure variable. |
b_out |
A vector of SNP effects on the outcome variable. |
Sig_inv_l |
A list of inverse of covariance matrix. |
theta |
A vector of final estimates of causal effect of each exposure by MVMR-cML-BIC obtained from |
zero_ind |
A vector of the index of valid IVs. |
r_vec |
A vector of estimated horizontal pleiotropic effects. |
Value
A vector
[Package MendelianRandomization version 0.10.0 Index]