Accessing and Processing a 'Mega2' Genetic Database


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Documentation for package ‘Mega2R’ version 1.1.0

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applyFnToGenes apply a function to the genotypes (markers) in each gene transcript and/or base pair range
applyFnToMarkers apply a function to the genotypes from a set of markers
applyFnToRanges apply a function to all the genotypes for markers found in several specified ranges
clean_mega2rtutorial_data remove tutorial data
computeDosage computeDosage function
dbmega2_import read Mega2 SQLite database into R
DOfamSKATRC DofamSKATRC call back function
DOpedgene pedgene call back function
DOSKAT SKAT call back function
dump_mega2rtutorial_data dump tutorial data
getgenotypes fetch genotype character matrix for specified markers
getgenotypesdos fetch dosage integer matrix for specified markers
getgenotypesgenabel process the genotype matrix for specified markers and return the corresponding GenABEL genotype matrix
getgenotypesraw fetch genotype integer matrix for specified markers
init_famSKATRC load Mega2 SQLite database and perform initialization for famSKATRC usage
init_pedgene load Mega2 SQLite database and perform initialization for pedgene usage
init_SKAT load Mega2 SQLite database and perform initialization for SKAT usage
Mega2ENVGenABEL generate gwaa.data-class object
Mega2famSKATRC execute the CRAN famSKAT_RC function on a subset of the gene transcripts
Mega2gdsfmt transcode mega2 to gdsfmt/SNP_ARRAY
Mega2GenABEL generate gwaa.data-class object from a *Mega2R* database
Mega2GenABELtst compare two gwaa.data-class objects
Mega2pedgene Execute the pedgene function on a transcript ranges
Mega2R-TBLS Mega2R SQLite3 tables
Mega2R-TBLSFilter Mega2R SQLite3 table filter
Mega2RVersion Mega2R version
Mega2SKAT execute the CRAN SKAT function on a subset of the gene transcripts
Mega2VCF generate a VCF file set for a collection of markers
mkfam assemble pedigree information into a data frame
mkMarkers create "markers" data frame
mkphenotype generate a phenotype data frame
read.Mega2DB load Mega2 database and initialize family data frame and markers data frame
setAnnotations set default name of transcription database and name of database mapping gene name to entrez gene id
setfam replace the pedigree data frame
setRanges set default range data: chromosome and start/end base pair
showMapNames show the association between mapno and mapname
showMega2ENV show Mega2R environment, viz. data frames and related info.
showPhenoNames show the association between index no and phenotype
TBLS Mega2R SQLite3 tables
TBLSFilter Mega2R SQLite3 table filter
uniqueFamMember regenerate fam data frame with unique values in member column
where_mega2rtutorial_data show directory of tutorial data