MotifEnrichment {MOCHA}

MotifEnrichment

Description

Test for enrichment of motifs within Group1 against a background Group2 using a hypergeometric t-test.

Usage

MotifEnrichment(Group1, Group2, motifPosList, type = NULL)

Arguments

Group1

A GRanges object, such as a set of significant differential tiles.

Group2

A GRanges object containing background regions, non-overlapping with Group1

motifPosList

A GRangesList of motifs and positions for each motif. Must be named for each motif.

type

Optional, name of a metadata column in Group1 and Group2 to test for enrichment the number of unique entries in column given by 'type'. Default is NULL, which tests the number of Ranges.

Value

A data.frame containing enrichment for each group