intervalVars {MAnorm2} | R Documentation |
Sample Variance of Replicated Signal Intensities
Description
Given a matrix of normalized signal intensities and the inverse of the
corresponding structure matrices, intervalVars
returns the sample
variance of signal intensities of each genomic interval.
Usage
intervalVars(x, inv.strMatrix)
Arguments
x |
A matrix of normalized signal intensities, where each row represents an interval and each column a sample. |
inv.strMatrix |
A list of inversed structure matrices corresponding to the intervals. Elements of it are recycled if necessary. |
Value
A numeric vector of the sample variances.
Note
For the i
th interval, ti * Si
is the covariance matrix
of the signal intensities of the interval, where ti
is a scalar
quantifying the variation level of these signal intensities (under this
biological condition), and Si
is the interval's structure
matrix (under this biological condition). intervalVars
returns
exactly the sample estimate of each ti
.
See Also
bioCond
for creating an R object representing a
biological condition, and setWeight
for modifying the
structure matrices of such an object.