Heritability of Gene Expression for Next-Generation Sequencing


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Documentation for package ‘HeritSeq’ version 1.0.2

Help Pages

computeVPC.CP Calculate the compound Poisson (CP) variance partition coefficient (VPC) for one or more features.
computeVPC.NB Calculate the negative binomial (NB) variance partition coefficient (VPC) for one or more features.
fit.CP Fit compound Poisson mixed effect models (CPMM) for one or more features.
fit.NB Fit negative binomial mixed models (NBMM) for one or more features.
fitComputeVPC.lmer Fit linear mixed models (LMM) and compute the VPC values for one or more features.
getBootCI Compute variance partition coefficition (VPC) confidence intervals (CI) for one or more features.
getReadMatrix.CP Simulate a read matrix from compound Poisson mixed effect models (CPMM).
getReadMatrix.NB Simulate a count matrix from negative binomial mixed effect models (NBMM).
para_cp Parameter matrix obtained from simData by fitting CPMM.
para_nb Parameter matrix obtained from simData by fitting NBMM.
simData A simulated sequencing dataset.
simData_voom Voom transformed version of simData.
simData_vst Variance stabilize transformed version of simData.
strains List of strain names for the samples.
weights_voom Weights used in the voom transformation.