createSimulationSettings {EvidenceSynthesis} R Documentation

## Create simulation settings

### Description

Create an object specifying a simulation. Currently only Cox proportional hazard models are supported.

### Usage

createSimulationSettings(
nSites = 5,
n = 10000,
treatedFraction = 0.2,
nStrata = 10,
minBackgroundHazard = 2e-07,
maxBackgroundHazard = 2e-05,
hazardRatio = 2,
randomEffectSd = 0
)


### Arguments

 nSites Number of database sites to simulate. n Number of subjects per site. Either a single number, or a vector of length nSites. treatedFraction Fraction of subjects that is treated. Either a single number, or a vector of length nSites. nStrata Number of strata per site. Either a single number, or a vector of length nSites. minBackgroundHazard Minimum background hazard. Either a single number, or a vector of length nSites. maxBackgroundHazard Maximum background hazard. Either a single number, or a vector of length nSites. hazardRatio Hazard ratio. randomEffectSd Standard deviation of the log(hazardRatio). Fixed effect if equal to 0.

### Value

An object of type simulationSettings, to be used in the simulatePopulations() function.

### Examples

settings <- createSimulationSettings(nSites = 1, hazardRatio = 2)
populations <- simulatePopulations(settings)

# Fit a Cox regression for the simulated data site:
cyclopsData <- Cyclops::createCyclopsData(Surv(time, y) ~ x + strata(stratumId),
data = populations[[1]],
modelType = "cox")
cyclopsFit <- Cyclops::fitCyclopsModel(cyclopsData)
coef(cyclopsFit)

# (Estimates in this example will vary due to the random simulation)



[Package EvidenceSynthesis version 0.3.0 Index]