Chen_2016_event_time_abovetime0 {EventPredInCure}

Function to generate event time based on Chen 2016 method for ongoing subject

Description

generate event time under the delay-treatment effect and cured population setting given T>time0

Usage

Chen_2016_event_time_abovetime0(u, distribution, p, time0, a, b, mu, sd)

Arguments

u

a scalar with between 0 and 1

distribution

the distribution for the control arm, valid values of inputs include: exponential, weibull, log-normal, log-logistic

p

the proportion of cured population in the control arm

time0

the observed ongoing survival time

a

the shape parameter in the Weibull or the log-logistic distribution

b

the scale parameter in the exponential, Weibull or the log-logistic distribution

mu

the mean in the log-normal distribution

sd

the standard deviation in the log-normal distribution

Value

the event time

References

• Chen, Tai-Tsang. "Predicting analysis times in randomized clinical trials with cancer immunotherapy." BMC medical research methodology 16.1 (2016): 1-10.