normsegs {CNprep} | R Documentation |
A reference set of segments
Description
A table of segment lengths and log copy number ratios for a large set of human diploid genomes.
Usage
data(normsegs)
Format
A data matrix with 43497 rows/segments and 2 columns/variables.
length
a numeric vector of segment genomic length
segmedian
a numeric vector of segment median computed from log copy number ratio
Details
The table originates in a set of copy number profiles of over a 1000 individuals, obtained using Representational Oligonucleotide Microarray Analysis (ROMA) technology. To ensure ploidy of 2 segments from X and Y chromosomes and segemnts shorter than 5Mb were excluded.
Source
Science. 2007 Apr 20;316(5823):445-9. Epub 2007 Mar 15.
Strong association of de novo copy number mutations with autism.
Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, Yamrom B, Yoon S, Krasnitz A, Kendall J, Leotta A, Pai D, Zhang R, Lee YH, Hicks J, Spence SJ, Lee AT, Puura K, Lehtimaki T, Ledbetter D, Gregersen PK, Bregman J, Sutcliffe JS, Jobanputra V, Chung W, Warburton D, King MC, Skuse D, Geschwind DH, Gilliam TC, Ye K, Wigler M.
Examples
data(normsegs)