| drugTarget {CINNA} | R Documentation |
Drug Target Network
Description
A bipartite graph extracted from DrugBank 1.0 database. The network includes two set of nodes including Food and Drug Administration (FDA)-approved drugs and their corresponding protein targets designated by their Uniprot ID. The 1080 drugs and their 519 target proteins nodes are connected via 3766 interactions. Please note that it is a shrunken network in which metabolizing enzymes, carriers and transporters associated with drug metabolism are filtered and solely targets directly related to their pharmacological effects are included. It is also an example of unconnected graphs.
Usage
drugTarget
Format
an igraph object with "gml" format
References
Barneh, F., Jafari, M., & Mirzaie, M. (2015). Updates on drug–target network; facilitating polypharmacology and data integration by growth of DrugBank database. Briefings in Bioinformatics, bbv094. https://doi.org/10.1093/bib/bbv094
Examples
data("drugTarget")
print(drugTarget)