Toolkit to Identify Candidate Synthetic Lethality

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Documentation for package ‘BiSEp’ version 2.3

• DESCRIPTION file.
• User guides, package vignettes and other documentation.

Help Pages

BiSEp-package	BiSEp: Bimodality in gene expression to dissect tumours and reveal synthetic lethal drug targets and biomarkers
BEEM	BEEM: Bimodal Expression Exclusive with Mutation
BIGEE	BIGEE: Bimodal Gene Expression Exclusivity.
BISEP	BISEP: Bimodality in Gene Expression data.
BiSEp	BiSEp: Bimodality in gene expression to dissect tumours and reveal synthetic lethal drug targets and biomarkers
BISEP_dat	A list object containing 3 data frames.
BISEP_data	A list object containing 3 data frames.
expressionPlot	expressionPlot: Create visualisations from BIGEE output
FURE	FURE: Functional redundancy between synthetic lethal gene pairs
FURE_data	Output matrix from the BIGEE tool
INPUT_data	A Log2 Gene Expression matrix
MUT_data	A matrix containing discreet mutation calls
waterfallPlot	waterfallPlot: Create visualisations from BEEM output