baseline_sampling {BICORN}

Gene Baseline Expression Sampling Function

Description

Function 'baseline_sampling' estimates a baseline expression for each gene, according to a posterior Gaussian distribution.

Usage

baseline_sampling(Y, C, A, X, base_line_old, C_prior, sigma_noise, sigma_A,
  sigma_baseline, sigma_X)

Arguments

Y

gene expression data matrix

C

sampled TF-gene binding network

A

sampled regulatory strength matrix

X

sampled transcription factor activity matrix

base_line_old

prior gene expression baseline activity

C_prior

prior TF-gene binding network

sigma_noise

variance of gene expression fitting residuals

sigma_A

variance of regulatory strength

sigma_baseline

variance of gene expression baseline activity

sigma_X

variance of transcription factor activity