A_sampling {BICORN} | R Documentation |
Function 'A_sampling' estimates a regulation strength for each sampled binding event in C, according to a posterior Gaussian distribution.
A_sampling(Y, C, A_old, X, base_line, C_prior, sigma_noise, sigma_A,
sigma_baseline, sigma_X)
Y |
gene expression data matrix |
C |
sampled TF-gene binding network |
A_old |
regulatory strength sampled from the previous round, used as a prior in current function |
X |
sampled transcription factor activity matrix |
base_line |
sampled gene expression baseline activity |
C_prior |
prior TF-gene binding network |
sigma_noise |
variance of gene expression fitting residuals |
sigma_A |
variance of regulatory strength |
sigma_baseline |
variance of gene expression baseline activity |
sigma_X |
variance of transcription factor activity |