pFstop {BDP2} | R Documentation |

## Operating characteristics of a single-arm trial with a binary endpoint with futility stopping

### Description

Determines the operating characteristics of a single-arm trial with a binary endpoint (success - failure) on the basis of analytical derivations. The design allows for futility stopping. Outputs are

probability of futility stopping (P.futil) at each interim analysis

cumulative stopping probability up to the interim (P.futil.cum).

### Usage

```
pFstop(p, vn.int, v.crit)
```

### Arguments

`p` |
true response rate |

`vn.int` |
vector of sample sizes at the interim analyses |

`v.crit` |
vector of critical boundaries for futility stopping at the interim analyses (stop for futility if number of successes <= boundary). Choose boundary=-1 if no stopping is allowed. |

### Examples

```
pFstop(p=0.3,vn.int=c(3,9,13,18,20),v.crit=c(0,1,2,3,3))
```

[Package

*BDP2*version 0.1.3 Index]