getStats {volcanoPlot}

Get Summary AE Statistics

Description

Compares reference and comparison groups to calculate group-wise metrics and p-values for use in AE volcano plot.

Usage

getStats(dfAE, dfDemog, settings, stat = "Risk Ratio")

Arguments

dfAE

Adverse events dataset structured as 1 record per adverse event per subject

dfDemog

Subject-level dataset

settings

Named list of settings (see examples below for standard list)

stat

Statistic to calculate for AE plot. Options are risk ratio ("RR" or "Risk Ratio"), risk difference ("RD" or "Risk Difference"). Defaults to "Risk Ratio".

Value

a data frame of group-wise statistics for use in the volcano plot

Examples

settings<-list(
  stratification_col="AEBODSYS",
  group_col="ARM",
  reference_group="Placebo",
  comparison_group="Xanomeline High Dose",
  id_col="USUBJID"
)
getStats(dfAE=safetyData::adam_adae, dfDemog = safetyData::adam_adsl, settings)