obs.y |
Observed data matrix with l rows and 4 columns. Row k in the matrix
represents the observed data from dose level k . The columns are
column 1: number of patient with no DLT, no immune response
column 2: number of patient with no DLT, immune response
column 3: number of patient with DLT, no immune response
column 4: number of patient with DLT, immune response
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prob.mdl |
Option of the probability models:
NONPARA: non-parametric+ model
NONPARA+: non-parametric model
PARA: partially parametric model
PARA+: partially parametric+ model
Default value is NONPARA . See visit for details.
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priors |
A class VTPRIOR object created by
vtPriorPar for PARA and PARA+ model.
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etas |
Vector of length 2 representing (p_L, p_U) . p_L : lower
bound of DLT risk, below which the current dose is considered absolutely
safe; p_U : upper bound of DLT risk above which the current dose is
considered too toxic
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prev.res |
Response rate from the next lower dose level, say, l-1 .
This can be a scalar representing the mean of the response rate
E(q^{(l-1)}) , or a vector of posterior samples of the response rate
q^{(l-1)} . For l=1 , this value is set to 0 .
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dec.cut |
Thresholds C_1,C_2,C_3 . If the vector length is shorter
than 3 , it is repeated to have 3 elements. See
visit for details.
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digits |
Digits for print
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seed |
Random seed
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... |
Reserved parameters
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