sPwRholmye {triggerstrategy}

Power of testing the secondary hypothesis using Holm-Ye

Description

This function computes the power of testing the secondary hypothesis using Holm-Ye

Usage

sPwRholmye(
  alpha,
  alpha0,
  t0,
  t1,
  tc0 = t0,
  tc1 = t1,
  delta0,
  delta1,
  rho = 0,
  iuse0 = 1,
  iuse1 = 1,
  phi0 = rep(1, length(alpha)),
  phi1 = rep(1, length(alpha))
)

Arguments

alpha

a number shows the overall error rate

alpha0

a number shows the error rate assigned to the primary endpoint initially

t0

a vector shows the information times of the primary endpoint

t1

a vector shows the information times of the secondary endpoint

tc0

a vector shows the calendar times of the primary endpoint

tc1

a vector shows the calendar times of the secondary endpoint

delta0

a value of delta for hypothesis H0

delta1

a value of delta for hypothesis H1

rho

a number shows the correlation between the primary and secondary endpoints

iuse0

an integer shows the type of group sequential boundaries used for the primary endpoint

iuse1

an integer shows the type of group sequential boundaries used for the secondary endpoint

phi0

a parameter for the power family or the HSD gamma family for the primary endpoint

phi1

a parameter for the power family or the HSD gamma family for the secondary endpoint

Value

a number shows the statistical power of rejecting H1

Examples

alpha <-  0.025
alpha0 <- 0.01
iuse0 <- 4
iuse1 <- 4
phi0 <- -4
phi1 <- -4
tc0 <- c(3,6,9,12,18)
tc1 <- c(6,12,18,36)
t0 <- (1:5)/5
t1 <- (1:4)/4
rho <- 0.5
delta0 <- 1
delta1 <- 3
sPwRholmye(alpha=alpha, alpha0=alpha0, 
    t0=t0, t1=t1, tc0=tc0, tc1=tc1, 
    delta0=delta0, delta1=delta1, 
    rho=rho, iuse0=iuse0, iuse1=iuse1, 
    phi0=phi0, phi1=phi1)