SMR {survexp.fr}R Documentation

Standardized Mortality Ratio (SMR)

Description

Computes the SMR, its confidence interval and its associated p-value

Usage

SMR(
  futime,
  status,
  age,
  sex,
  entry_date,
  ratetable = survexp.fr::survexp.fr,
  alpha = 0.05
)

Arguments

futime

follow-up time of the subjects in days

status

0 if censored or 1 if dead at futime

age

age in days

sex

"male" or "female"

entry_date

entry date in the study

ratetable

a table of event rates, such as survexp.fr or survexp.us

alpha

determines the confidence level (1-alpha) of the confidence interval

Details

The SMR is estimated using two different methods.

The classic method is:

SMR=O/ESMR = O/E

where OO is the observed number of deaths and EE is the expected number based on the patients' characteristics (sex, age and entry date in the study).

The SMR is also estimated performing a Poisson model where OO is the dependant variable and EE is an offset.

Value

A list containing the observed number of deaths, the expected number of deaths, the "classic" SMR (with its confidence interval and its p-value) and the SMR calculated by a Poisson model (with its confidence interval and its p-value)

Author(s)

Jean-Philippe Jais and Hugo Varet

References

N. Breslow and N. Day, Statistical methods in cancer research, Volume II - The design and analysis of cohort studies, World Health Organization, 1987

Examples

attach(data.example)
SMR(futime, status, age, sex, entry_date)

[Package survexp.fr version 1.1 Index]