hwe {survSNP} | R Documentation |
Relative genotypic frequencies under HWE
Description
Compute relative genotypic frequencies for a given relative allelic frequency
Usage
hwe(raf)
Arguments
raf |
Relative minor allele frequency for the B allele. |
Details
For a bi-allelic SNP with genotypes AA, AB and
BB,
with a relative allele frequency q
for the B allele,
this function returns the corresponding relative genotypic
frequencies.
It is not intended to be called directly by the user.
To conduct power calculations, use sim.snp.expsurv.power
or the convenience wrapper function survSNP.power.table.
Value
A vector of length three relative genotypic frequencies.
Author(s)
Kouros Owzar, Zhiguo Li, Nancy Cox, Sin-Ho Jung and Chanhee Yi
References
Kouros Owzar, Zhiguo Li, Nancy Cox and Sin-Ho Jung. Power and Sample Size Calculations for SNP Association Studies with Censored Time-to-Event Outcomes. https://onlinelibrary.wiley.com/doi/full/10.1002/gepi.21645
Examples
censbnd(0.1,hwe(0.1),0.9)