sumFREGAT-package {sumFREGAT}

sumFREGAT: Fast REGional Association Tests on summary statistics

Description

The sumFREGAT package computes the most popular and efficient tests for the region-based association analysis using summary statistics data (beta and P values) and correlations between genetic variants. It does not require genotype or phenotype data. Methods implemented are SKAT and SKAT-O (sequence kernel association tests), BT (burden test), ACAT (aggregated Cauchy association test), FLM (functional linear model), PCA (principal components analysis), and others.

Details

Package: sumFREGAT
Type: Package
License: GPLv3

Author(s)

Nadezhda Belonogova <[e-mail]>
Gulnara Svishcheva <[e-mail]>

The authors are grateful to Dr. Anatoly Kirichenko for technical support
and Prof. Tatiana Axenovich for scientific guidance.