stressaddition-package {stressaddition}R Documentation

stressaddition: Modelling Tri-Phasic Concentration-Response Relationships

Description

The stress addition approach is an alternative to the traditional concentration addition or effect addition models. It allows the modelling of tri-phasic concentration-response relationships either as single toxicant experiments, in combination with an environmental stressor or as mixtures of two toxicants. See Liess et al. (2019) <doi:10.1038/s41598-019-51645-4> and Liess et al. (2020) <doi:10.1186/s12302-020-00394-7>.

Details

This R package contains the definitions of the ECx-SyS model and the Multi-TOX model. See the publications linked below for more information including equations.

Author contributions: M. Liess conceived the ECx-SyS and Multi-TOX models. S. Henz developed this R package. N. Shahid contributed to the optimization of the Multi-TOX model and provided the multiple_stress data set.

Author(s)

Maintainer: Sebastian Henz bastihz.dev@posteo.de (ORCID)

Authors:

Other contributors:

References

Liess, M., Henz, S. & Knillmann, S. Predicting low-concentration effects of pesticides. Sci Rep 9, 15248 (2019).

Liess, M., Henz, S. & Shahid, N. Modeling the synergistic effects of toxicant mixtures. Environ Sci Eur 32, 119 (2020).

See Also

Useful links:


[Package stressaddition version 3.1.0 Index]