Single-Sample Mutation-Based Pathway Analysis


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Documentation for package ‘ssMutPA’ version 0.1.0

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cox_data cox_data Univariate cox proportional hazards regression data.
dotplot Plotting the Dot plot .
dot_data dot_data A data frame.
FastSEAscore Calculate the enrichment score of the pathways .
get_heatmap Plotting a heatmap with subtype labels.
get_indicate Indicator function.
get_mut_status Converts MAF file or data in other formats into mutation matrix.
get_RWR_ES Calculate the single-sample mutation-based pathway enrichment score.
get_samp_class Determining cancer subtypes using unsupervised spectral clustering algorithm.
get_seeds_score Calculate the local wight of seed nodes.
get_univarCox_result Perform the univariate Cox proportional hazards regression analysis.
mountain_plot Plotting the density ridges plot.
MRWR A global propagation algorithm, random walk with restart (RWR), to predict probable influence of nodes in the network by seed nodes.
mut_onco mut_onco A binary mutation matrix.
mut_status mut_status A binary mutation matrix.
Oncoplot Drawing a waterfall plot of a particular pathway.
Path_ES Path_ES Single-sample mutation-based pathway enrichment score profiles.
Path_Name Path_Name
RWR_res RWR_res Random walk results based on mutated genes in a single sample.
sample_class sample_class The subtype labels of samples.
samp_class_onco samp_class_onco
Seeds_Score Seeds_Score The local weight of seed nodes.
sur_onco sur_onco